Township firefighters responded to the 700 block of Lillian Lane around 10:30 p.m. on May 20, police said in a release.
They arrived to find smoke and a wet floor in the basement with a fire still raging inside the walls, officials said.
Investigators believe the fire started when a meth cooking operation exploded in the basement bathroom, police said. A state police team was called in to help dismantle the scene.
The investigation is still ongoing and anyone with information is asked to call 215-672-1000 or submit a tip on Crimewatch.
Click here to follow Daily Voice Plumstead-Pipersville and receive free news updates.